As mentioned in the Strategic Vision Section, NC State University has a strong environmental health science
research base that has been drawn together and organized into a center that will facilitate and promote
synergies among investigators creating an environmental health research focus that has an impact much greater than a sum of the individual investigators.
The CHHE faced the challenge of developing an effective translation component at a land grant institution that is without a medical school or school of public health. The mission of IHSFC is the successful development of a CHHE translation component to link basic research findings to public health outcomes, to advance clinical collaborations and to obtain human samples will be critical to provide new opportunities to CHHE investigators. To accomplish this the IHSFC will be at the core of a bidirectional interaction between each of the central CHHE components: rural community health; community outreach and engagement; and CHHE research initiatives. Figure 1 illustrates our vision for the synergistic interactions among the central components of the Center and the interface with IHSFC. CHHE leaders have worked to develop important, relevant partnerships that will produce an effective and relevant translational IHSFC. CHHE has developed six IHSFC partnerships/linkages that will promote the mission of CHHE and initiate and enhance translational research. The six components are:
• Agricultural Health Study (Dr. Jane Hoppin, NIEHS)
• North Carolina Translational and Clinical Sciences Institute (Drs.Richard Davis,Michelle Henandez And David Peden UNC-CH)
• NC Department of Health and Human Services, Division of Public Health (Dr. Ricky Langley)
• East Carolina University (ECU) Brody School of Medicine, Department of Public Health (DPH) and NC Agromedicine Institute (Dr. Gregory Kearney ECU).
• Comparative Toxicogenomics Database (Dr. Carolyn Mattingly, NC State)
• Community Outreach and Engagement CHHE (Dr. W. Gregory Cope, NC State)
Each component has a designated leader(s) who will serve as a Liaison(s), and act as collaborators/navigators for CHHE member interactions as described below. Although the CHHE and the IHSFC are still in its early stages of development, a number of fruitful collaborations have already grown from the natural linkages that exist within the community of scientists that are the foundation for this application. Specific examples of the success of these linkages can be found on the last two pages of this core description.
- To foster collaborative efforts among basic scientists, epidemiologists, clinical researchers, and public health practitioners that will impact our understanding and prevention of the adverse effects of environmental factors on human health.
- To facilitate translational research that will enhance translation of basic research findings into practical applications for patients and communities.
Through the three-pronged IHSFC, CHHE will achieve the IHSFC’s objectives. Importantly, we envision that the IHSFC will be at the core of a bidirectional interaction between each of the central CHHE components: rural community health; community outreach and engagement; and CHHE research initiatives. Figure 1 illustrates our vision for the synergistic interactions among the central components of the Center and the interface with IHSFC.
Dr. Philip Sannes, PhD Director IHSFC, Professor of Molecular Biomedical Sciences, NC State University
Dr. W. Gregory Cope, PhD COEC Liaison, Environmental and Molecular Toxicology, NC State University
Dr. Richard Davis, MD NC TraCs Liaison, Research Navigator NC Tracs, Co-Director, UNC Center for Diabetes Translation Research
Dr. Michelle Hernandez, MD NC TraCs Liaison Pediatrics, Division of Allergy, Immunology, Rhematology and Infectious Diseases, University of North Carolina, Chapel Hill
Dr. Jane Hoppin, ScD Environmental Epidemiologist , NIEHS (Adjunct Professor, NC State)
Dr. Gregory D. Kearney, DPH ECU Liaison, Public Health, East Carolina University School of Medicine
Dr. Ricky Langley, MD MPH Public Heath Physician, NC Department of Health and Human Service (NC DHHS) Division of Public Health (Adjunct Professor, NC State)
Dr. Carolyn Mattingly, PHD CTD Liaison, Comparative Toxicogenomics Database, NC State University
Dr. David B. Peden, MD, MS Clinical Advisor, NC Translational and Clinical Science Institute (NC TraCs) Pediatrics, Medicine and Microbiology/Immunology at the University of North Carolina at Chapel Hill