CHHE has developed three Facility Cores that will significantly increase the impact and the basic science and translational capacity of its Research Teams. One CHHE Core (Systems Technologies Core) provides cutting-edge technologies involving proteomics, metabolomics, and genomics along with dedicated bioinformatics support; another (Comparative Pathology Core) provides pathologic phenotypic assessment of the many model organisms used by CHHE investigators and provides laser capture microdissection service with links back to the “omics” technologies. The third core, the Integrative Health Sciences Facility Core, enables CHHE investigators to translate basic science discoveries to clinical and public health outcomes and vice versa.