The Metallomics, Metabolomics and Small Molecules Sections within the Systems Technologies Core (STC) provide elemental analysis of metals as well as workflows for analyzing the low molecular weight complement of cells, tissues, or biological fluids.  Metabolomics makes it feasible to uniquely profile the biochemistry of an individual, or system, apart from, or in addition to, the genome and proteome.  The metabolomics profile includes signals for endogenous compounds, and exogenously derived components (e.g., metals, chemicals, and drugs), and can include study designs to examine metabolic flux. Metabolomics is used to determine the pattern of changes (and related metabolites) arising from disease, dysfunction, disorder, or from the therapeutic or adverse effects of xenobiotics. These studies can be conducted via various sample matrices (e.g., biofluids, environmental samples).


The Metallomics, Metabolomics and Small Molecules Sections can consult on and conduct various studies with CHHE members: