Welcome to the CHHE Knowledge Base (CHHEK). This site is designed to support the CHHE community with information about other members, shared resources, and summary statistics about our diverse research community.
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James Bonner
Professor
NC State
College of Sciences
https://orcid.org/0000-0002-4574-9782
(919) 515-8650
https://bonnerlab.wordpress.ncsu.edu/
Our goal is to explore and identify mechanisms of environmental lung diseases (asthma, fibrosis, cancer) caused by emerging toxicants that pose a threat to human health and the environment. A major part of our work is focused on investigating mechanisms of pulmonary toxicity caused by engineered nanomaterials; tiny particles or fibers designed at the atomic scale that are increasingly used in a variety of applications. Of particular interest is determining the toxic potential of nanomaterials in susceptible populations and individuals with pre-existing disease, especially asthma.
- Bioinformatics
- Biostatistics
- Cell biology
- Exposure assessment
- Genomics
- Immunology
- Molecular biology
- Pathology
- Physiology
- Proteomics
- Toxicology
- Cell culture
- Cell signaling (receptors, kinases, etc.)
- ELISA/RIA
- Environmental pollution
- Experimental design - pathology considerations
- Histology
- PCR quantitative/real-time
- Reactive oxygen species
- Western blot
- In vitro/cell culture
- Mice
- Aeroallergens
- Air pollution
- Fluorinated compounds (per- or poly)
- Nanoparticles