Michael Cowley

Bio

The goals of the Cowley Lab are to understand how the developmental environment impacts the epigenetic regulation of the genome, and to understand the functional consequences of this for development and disease.

Research Impact Dashboard

Publications

• Cadmium exposure during adolescence and young adulthood induces signatures of metabolic dysfunction-associated steatotic liver disease , Scientific Reports (2025)
• Dietary Iron Supplementation Protects Against Growth Restriction and Metabolic Dysfunction-Associated Steatotic Liver Disease in Perinatal Cadmium-Exposed Mice , FASEB BIOADVANCES (2025)
• Environmental Contaminants, Iron Deficiency, and Iron‐Deficiency Anemia: A Review of the Literature , Scientifica (2025)
• The effects of developmental cadmium exposure on health and disease , DISEASE MODELS & MECHANISMS (2025)
• Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism , BMC BIOLOGY (2024)
• LncRNA Tuna is activated in cadmium-induced placental insufficiency and drives the NRF2-mediated oxidative stress response , FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2023)
• Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction , EPIGENETICS (2022)
• Genomic map of candidate human imprint control regions: the imprintome , EPIGENETICS (2022)
• The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease , TOXICOLOGICAL SCIENCES (2022)
• Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome , HEPATOLOGY (2022)