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Awarded Pilot Projects

DateAwardeeProject TitleBudget
2023/09Sarah Rhea, Dept. of Population Health and Pathobiology, NC StateInvestigating the Relationship Between Serum Folate and PFAS Levels in a Population with Known PFAS Exposure$25,000
2023/09Yang Zhang, Dept. of Textile Engineering, Chemistry and Science, NC StateEstablishing a Super-resolution Optical Imaging Platform to Decode the Nanoscale Organizations and Interactions Among Higher-order Chromatin Structures and Epigenetic Marks$25,000
2023/09James Bonner, Dept. of Biological Sciences, NC StateImpact of Wildfire Smoke Particles and Combustion-Derived Microplastic Particles on Allergen-Induced Lung Disease in Mice$25,000
2023/09Xinxia Peng, Dept. of Molecular Biomedical Sciences, NC StateLong-term Impact of Gestational PFAS Exposure on Immune Repertoire Development and Transcriptional Regulation$25,000
2023/09Natalia Duque-Wilckens, Dept. of Biological Sciences, NC StateEvaluating the Potential of Mast Cells as Key Drivers of Increased Susceptibility to Physical and Psychological Disease Resulting from Perinatal Exposure to Flame Retardants$25,000
2023/03Cathrine Hoyo & Shobhan Gaddameedhi, Dept. of Biological Sciences, NC StateNight Shift Work as an Environmental Carcinogen: Insights into Circadian Control of Epigenetic DNA Methylation Patterns in Cancer Hallmark Genes$50,000
2023/03Katie Sheats, Dept. of Clinical Sciences, NC StateUsing Sentinel Animals to Determine the Impact of Particulate Air Pollution of Asthma: A Phenotypic, Bioenergetic and Proteomic Analysis of BAL Samples from Asthmatic Horses Living Outdoor$25,000
2023/03Xiaojing Liu, Dept. of Molecular and Structural Biochemistry, NC StateInvestigating the Role of Gut-liver Axis in Herbicide-induced Metabolic$25,000
2023/03Ayse Ercumen & Mirela Tulbure, Dept. of Forestry and Environmental Resources, NC StateEarth Observation Data to Support Environmental Justice: Linking Non-permitted Poultry operations in North Carolina to Water Quality Impacts and Environmental Vulnerability Indice$50,000
2022/09Hong Wang, College of Sciences, NC StateHigh-speed AFM imaging of the SMC5/6 complex encountering DNA repair intermediate structures
2022/09John Bang, Environmental, Earth and Geospatial Sciences & TinChung Leung, Biological and Biomedical Sciences, North Carolina Central UniversityHealth Impacts of Micro and Nano Plastics (MNPs): Delineating Embryotoxicity profiles of Zebrafish through Identifying Critical Physicochemical Properties of Representative MNPs families
2022/09Tal Ben-Horin, College of Veterinary Medicine & Scott Belcher, College of Sciences, NC StateToxin mixtures in coastal ecosystems and accumulation in farmed shellfish
2022/03
Jeffrey A. Yoder, Dept. of Molecular Biomedical Sciences, NC StateAssessing the impact of PFAS exposure on neutrophil function and microbial infection
2022/03
Tatyana I. Smirnova, Dept. of Chemistry, NC StateOxidant Exposure by Electronic Nicotine Delivery Systems and Heated Tobacco Products
2022/03
Jingjie Hu, Dept. of Mechanical and Aerospace Engineering, NC StateInvestigating the effect of pulmonary surfactant on the adhesive interactions between nanoparticles and living cells by atomic force microscopy and endocytosis modeling
2022/03
Glenn Cruse, Dept. of Molecular Biomedical Sciences, NC StateInvestigating the Effect of Exposure to Per- and Polyfluoroalkyl Substances (PFAS) on Human Mast Cell Activation and Gene Expression
2022/03
Michael Cowley, Dept. of Biological Sciences, NC StateThe role of Hox regulation in neurodevelopmental toxicity of prenatal cadmium exposure
2022/03
Seth Kullman, Dept. of Biological Sciences, NC State & David Collier, Brody School of Medicine, East CarolinaVitamin D, Endocannabinoid Tone and Obesity: the VETO Study
2022/03
Srijan Sengupta, Dept. of Statistics & Viney Aneja, Dept. of Marine, Earth, and Atmospheric Sciences, NC StateWildfire pollution exposure and human health: Building a novel AI-powered air quality forecasting model for a growing public health issue
2021/09Shobhan Gaddameedhi, Dept. of Biological Sciences and Toxicology Program, NC StateNight Shift Work as an Environmental Carcinogen: Molecular Mechanisms and Biomarkers
2021/03Amay Bandodkar, Dept. of Electrical and Computer Engineering
& Santosh Mishra, Dept. of Molecular Biomedical Sciences, NC State
Wireless, spinal cord-interfaced, subdermal microsensors for studying the effects of environmental factors on atopic dermatitis-induced neural signaling
2021/03Alon Greenbaum, Dept. of Biomedical Engineering & Kenneth Adler, Dept. of Molecular Biomedical Sciences, NC StateInvestigating the effects of secondhand smoke from E-cigarettes on mice lungs through 3D-imaging and novel exposure generation system
2021/03Aaron Hipp, Dept. of Parks, Recreation and Tourism Management, NC StateInvestigating the impact of environmental greenspace exposure on telomere length
2021/03TinChung Leung, Dept. of Biological and Biomedical Sciences & Deepak Kumar, Dept. of Pharmaceutical Sciences, NCCUUsing zebrafish chemical screens to assess impact of per- and polyfluoroalkyl substances (PFAS) on accelerating the aging process
2021/03Balaji Rao & Albert Keung, Dept. of Chemical and Biomolecular Engineering, NC StateEnvironmental effects on placenta-to-brain communication
2021/03Coby Schal & Madhavi Kakumanu, Dept. of Entomology and Plant Pathology, NC StateEmerging pest-associated biocontaminants in North Carolina households
2021/03Astrid Schnetzer, Dept. of Marine Earth and Atmospheric Science & Tal Ben-Horin, Dept. of Clinical Sciences, NC StateCyanotoxin exposure from shellfish consumption in NC coastal waters
2021/03Xiaoqiu Wang, Dept. of Animal Science, NC StateIdentifying uterine specific enhancer and transcription machinery for leukemia inhibitory factor
2021/03Yi-Hui Zhou, Dept. of Biological Sciences, NC StateAn analysis platform to predict health-related outcomes from Ion mobility-mass spectrometry profiles
2020/09David L. Aylor & Michael L. Sikes, Dept. of Biological Sciences, NC StateThe Role of TIP30 in the Long-term Epigenomic Response to Early-life TCDD Exposure
2020/09Karen Litwa, Dept. of Anatomy and Cell Biology & Krista McCoy, Dept. of Biology, ECUDetoxifying a Toxic Environment: Investigating Sulforaphane-Mediated Prevention of Pollutant-Induced Neurodevelopmental Abnormalities
2020/09Markus Petters, Dept. of Marine, Earth and Atmospheric Sciences, NC StateInvestigation of the toxicity of sub-10 nm particles on bacterial cells from airborne samples at low mass concentration
2020/03Erin Baker, Dept. of Chemistry, NC StateInvestigating PFAS occurrence in private wells in North Carolina uniquely impacted by land-applied biosolids using a novel non-targeted analytical workflow
2020/03Jamie DeWitt & Tracey Woodlief, Dept. of Pharmacology and Toxicology, ECUUncovering PFOA-induced metabolic changes and their association with B-cell metabolic function
2020/03Jane Hoppin, Dept.of Biological Sciences, NC StateInvestigating immune system impacts of PFAS in a uniquely exposed population in North Carolina
2020/03Parminder Kaur & Hong Wang, Dept. of Physics, NC StateHigh-speed atomic force microscopy and DREEM imaging of DNA damage repair on chromatin
2020/03Santosh Mishra, Dept. of Molecular Biomedical Sciences & Thierry Olivry, Dept. of Clinical Sciences, NC StateInvestigations on the role of indoor environmental stressor house dust mite in atopic dermatitis
2020/03Helena Mitasova, Dept. of Marine, Earth and Atmospheric Sciences & Jane Hoppin, Dept. of Biological Sciences, NC StateA web platform for mapping global, publication based, spatial and temporal distributions of per and polyfluoroalkyl substances (PFAS)
2020/03Ryan Paerl, Dept. of Marine, Earth and Atmospheric Sciences, NC StateWho are the toxic cyanobacteria potentially impacting humans in the Chowan River?
2020/03Yoo Min Park, Dept. of Geography, Planning, and Environment & Sinan Sousan, Dept. of Public Health, ECUA low-cost mobile air-pollution sensor with geospatial mapping: A tool for community-engaged, environmental health disparity research
2020/03Qingshan Wei, Dept. of Chemical and Biomolecular Engineering & Yong Zhu, Dept. of Mechanical and Aerospace Engineering, NC StateContinuous Monitoring of Personal Health – Environment Interaction by a Wearable, Skin-Breathing Chemiresistive Sensor Array
2019/09Scott Belcher, Dept. of Biological Sciences, NC StateExploring fish consumption as a route of human Per- and polyfluoroalkyl substances (PFAS) exposure
2019/09Kurt Marsden & Michael Bereman, Department of Biological Sciences, NC StateCellular and molecular mechanisms of cyanotoxin mixture-induced neurotoxicity
2019/09S. Alex Marshall, Dept. of Biological and Biomedical Sciences, NCCUThe comorbid effects of arsenic exposure and alcohol abuse on hippocampal neurodegeneration
2019/09Mark Moss, School of Dental Medicine & David Collier, Pediatric Healthy Weight Research and Treatment Center, ECUEnvironmental Lead Surveillance to Improve Caries Risk Assessment in Primary Care
2019/09Roger Narayan, Dept. of Biomedical Engineering, NC State & Jonathan Thornburg, RTI InternationalNC STATE-RTI collaboration on multi-pollutant exposure monitor that measures real-time total PM and PM species
2019/09Tongde Wu, Dept. of Pharmaceutical Sciences, NCCUDegradation of Bacterial Permeability Family Member A1 (BPIFA1) by House Dust Mite (HDM) Abrogates Innate Immune Response
2019/03James Bonner, Dept of Biological Sciences, NC StateAssessing the Consequences of Inhalation Exposure to GenX on the Pulmonary Immune Response of Mice to Allergens and Microbial Agents
2019/03Delores J. Grant, Dept. of Biological and Biomedical Sciences, NCCUEpigenetic Dysregulation of Liver Detoxification Genes in Hepatocellular Carcinoma
2019/03Johanna L. Hannan, Dept. of Physiology & Kymberly Gowdy, Dept. of Pharmacology & Toxicology, ECUImpact of Acute and Chronic Ozone Exposure on Bladder Dysfunction
2019/03John Meitzen, Dept. of Biological Sciences, NC StateNeural Mechanisms of Social Disruption of the Flame Retardant Mixture Firemaster 550
2019/03Yoshiaki Tsuji & Jun Ninomiya-Tsuji, Dept. of Biological Sciences, NC StatePerturbation of Iron Homeostasis by Environmental Chemicals
2019/03Hong Wang, Dept. of Physics, NC StateDeciphering the Roles of Cohesin SA1 and SA2 in DNA Damage Response at Telomeres
2018/09Glenn Cruse, Dept. of Molecular Biomedical Sciences, NC State & Donald Feytes, Joint Dept. of Biomedical Engineering, UNC/NC StateA tissue‐specific model to study heterogeneous mast cell phenotype using extracellular matrix hydrogels
2018/09Michael P. Gamcsik, Dept. of Biomedical Engineering, NC StateAromatic Hydrocarbon-Induced Carcinogenesis in Multiple Oxygen Environments
2018/09Parminder Kaur & Hong Wang, Dept. of Physics, NC StateHigh-speed AFM imaging of the dynamics of mitochondrial DNA replication encountering DNA lesions
2018/09Edgar Lobaton & Alper BozKurt, Dept. of Electrical and Computer Engineering, NC StateFinding Correlations between Asthma Exacerbation, Physiological Measurements and Environmental Factors
2018/09Nanette Nascone-Yoder, Dept. of Molecular Biomedical Sciences, NC StateAtrazine and Left-Right Asymmetric Birth Defects
2018/09Emilie Rissman, Dept. of Biological Sciences, NC StateBisphenol exposure biases the developing brain towards drug addiction
2018/03Scott Belcher & Theresa C. Guillette, Dept. of Biological Sciences, NC StateGestational Effects of Low Dose Cd Exposure on Epigenetic Regulation of Metabolism
2018/03Michael Cowley & Marine Baptissart, Dept. of Biological Sciences, NC StateZac1 and the Imprinted Gene Network in the Programming of Non-Alcoholic Fatty Liver Disease
2018/03Kymberly M. Gowdy, Dept. of Pharmacology and Toxicology, ECUThe novel role for estrogen signaling in pulmonary eicosanoid metabolism after ozone exposure
2018/03Seth Kullman, Dept. of Biological Sciences, NC StateAre long non-coding RNAs the missing link in AhR mediated repression of mesenchymal stem cell differentiation?
2018/03Carolyn Mattingly, Dept. of Biological Sciences, NC StateGenX and related perfluorinated compounds: a comparative analysis of trophic transfer and toxicity
2018/03Xiaoping Pan, Dept. of Biology, ECUImpacts of GenX (2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)- propanoate) on reproductive function and transcriptome signature in Caenorhabditis elegans
2018/03Brian Reich, Dept. of Statistics, NC StateNovel statistical methods for estimating the health effects of chemical mixtures
2018/03Marcelo Rodriguez-Publa, Dept. of Molecular Biomedical Sciences & Michael Bereman, Dept. of Biological Sciences, NC StateA novel role of CDK4 in the transcriptional regulation of chromosome stability genes
2018/03Coby Schal & Zachary DeVries, Dept. of Entomology & Plant Pathology, NC StateHistamine in homes: Spatial distribution and exposure risks
2017Michael Bereman, Dept. of Biological Science, NC StateConstruction of 3 Dimensional Paper Microfluidic Devices for Detection of Toxins Present in Water Supplies
2017James Bonner, Dept. of Biological Sciences & Gregory Parsons, Dept. of Chemical and Biomolecular Engineering, NC StateDevelopment of a Predictive In vitro Bioassay to Screen Diverse Types of Carbon Nanotubes for Mesothelial Cell Transformation for Prevention of Mesothelioma
2017Glenn Cruse & Ken Adler, Dept. of Molecular Biomedical Sciences, NC StateDelivering Mast Cell Targeting Oligonucleotides to the Lung as a Therapeutic Strategy for Asthma
2017Parminder Kaur, Dept. of Physics, NC StateImpact of DNA Damage on Mitochondrial DNA Replication at the Single-Molecule Level
2017Heather Patisaul, Dept. of Biological Sciences, NC StateSex-Specific Placental Accumulation and Disruption by the Flame Retardant Firemaster 550
2017Antonio Planchart & Carolyn Mattingly, Dept. of Biological Sciences, NC StateElucidating the Connection Between Cadmium Mediated Hyperactivity and Down regulation of the E3 Ubiquitin Ligase, RNF2
2017Hongyu Ru, Dept. of Population Health and Pathobiology, NC State & Kun Lu, Dept. of Environmental Sciences and Engineering, UNC-CHMapping Serum Exposome of Human Inflammatory Bowel Diseases
2017Nelson Vinueza, Dept. Textile Engineering, Chemistry and Science, NC StateAllergic Contact Dermatitis from Disperse Dyes in Textiles
2017Xiaohe Yang, Dept. of Biological and Biomedical Sciences, NCCUEffects of In Utero Exposure to Bisphenol S on Pubertal Mammary Gland Development in MMTV-ErbB2 Transgenic Mice
2017Jeff Yoder, Dept of Molecular Biomedical Sciences, NC StateImmune Suppression by Pyrene Exposure
2017Fernando Garcia Menendez, Dept. of Civil, Construction, and Environmental Engineering & Joseph P. Roise, Dept. of Forestry and Environmental Resources, NC StateQuantifying Adverse Impacts of Smoke Exposure from the Fall of 2016 Southeast Wildfires on North Carolina Public Health
2017David N. Collier, Dept. of Pediatrics, ECU & Carolyn Mattingly, Dept. of Biological Sciences, NC StateBenzoic acid in beverages; Establishing a link between urinary metabolites, metabolic dysregulation and weight loss failure
2016/09Michael S. Bereman, Dept. of Biological Sciences, NC StateInvestigating the Interplay between Genetic and Environmental Mechanisms Underlying Amyotrophic Lateral Sclerosis Etiology
2016/09Jonathan R. Hall, Dept. of Biological Sciences, NC StateThe Role of C/EBPβ in Regulating p53 Pro-Apoptotic Transcriptional Activity in Response to UVB Solar Radiation
2016/09Krista A. McCoy, Dept. of Biology, ECU & Michael Bereman, Dept. of Biological Sciences, NC StateReducing Pollutant-Induced Hypospadias: is Nrf2 Driving the Rescue?
2016/09Melissa A. Pasquinelli & Rachelle Bienstock, Dept. of Textile Engineering, Chemistry, and Science, NC StateA Bioinformatics and Molecular Modeling Approach towards Understanding Epigenetic Targets and Genotoxic and Mutagenic Biological Pathways of Azo Dyes within Organisms
2016/09Emilie Rissman, Dept. of Biological Sciences, NC StateImpact of Phthalate Exposure on Paternal Programming of Offspring Neurological Phenotype
2016/09Yoshiaki Tsuji, Dept. of Biological Sciences, NC StateThe Role and Regulation of p66Shc by Nrf2 in Cellular Antioxidant Response to Xenobiotics
2016/03Zuzana Drobna, Dept. of Biological Sciences, NC StateBehavior and specific gene alterations after prenatal exposure to arsenic
2016/03Jodie M. Fleming, Dept. of Biology, NCCUMechanisms of nanoparticle endocytosis and the subsequent effects on extracellular matrix deposition and epithelial cell adhesion
2016/03Seth W. Kullman, Dept. of Biological Sciences, NC StateEstablishing a targeted genomic map of quantified transcriptional and epigenetic modifications associated with AhR mediated repression of mesenchymal stem cell differentiation
2016/03Jun Ninomiya-Tsuji, Dept. of Biological Sciences, NC StateEpigenetic modulation and hypothalamic leptin resistance in toxic metal exposures
2016/03Matthew Polizzotto, Dept. of Soil Science, NC StateArsenic treatment of contaminated water using surface-functionalized fabrics
2016/03Michael Sikes, Dept. of Biological Sciences, NC StateThe role of upstream stimulatory Factor in Tumor Suppression
2016/03Mary Jane Thomassen, Dept. of Internal Medicine, ECUCharacterization of pulmonary lymphocytes involved in exacerbation of environmental lung disease by microbial antigen
2016/03Hong Wang, Dept. of Physics, NC StateTelomeric cohesin complex and DNA damage induced telomere instability
2015David L. Aylor & Michael Bereman, Dept. of Biological Sciences, NC StateSystems toxicology in genetically diverse mouse cells
2015Michael A. Cowley & Michael Bereman, Dept. of Biological Sciences, NC StateEstablishment and implementation of a unique model for elucidating the mechanisms of action of endocrine disrupting compounds during early development
2015Jamie C. DeWitt, Dept. of Pharmacology and Toxicology, ECUDiscovery of biomarkers of effect following environmentally-relevant exposure to pharmaceutical pollutants
2015Christopher Frey, Dept. of Civil, Construction, and Environmental Engineering, NC StateDevelopment and demonstration of methods for measurement of human exposure to air pollution using portable sensors applied to high potential dose scenarios in urban environments
2015Travis W. Gannon, Dept. of Crop Sciences, NC State & Jane A. Hoppin, Dept. of Biological Sciences, NC StatePesticide exposure assessment of commercial lawn care operators
2015Jeffrey A. Yoder, Dept. of Molecular Biomedical Sciences & David M. Reif, Dept. of Biological Sciences, NC StateImmune-suppression by embryonic exposure to polycyclic aromatic hydrocarbons
2013Michael Bereman, Dept. of Biological Sciences, NC StateTowards an unbiased multiplex exposure assay – coupling ultra-high pressure liquid chromatography and data independent acquisition (DIA) mass spectrometry
2013Heather Patisaul, Dept. of Biological Sciences, NC StateMetabolic disrupting actions of the flame retardant mixture firemaster 550
2013Antonio Planchart, Dept. of Biological Sciences, NC StateCellular and molecular studies of inorganic arsenic-induced deficiencies in the innate immune system
2013Marcelo Rodriguez-Puebla, Dept. of Molecular Biomedical Sciences, NC StateImpact of transplacental arsenic exposure on keratinocyte stem cells
2013Hong Wang, Dept. of Physics, NC StateTRF1 and TRF2 in repair of UV-induced double-stranded DNA breaks
2012Michael Hyman, Dept. of Microbiology, NC StateProteomic analyses of oxygenase expression in trichloroethylene (TCE) –degrading Mycobacteria
2012Ricky L. Langley, NC Division of Public Health, DHHSInvestigation of potential neurotoxicological impacts associated with chronic ingestion of manganese in North Carolina ground water
2012Kathryn M. Meurs, Dept. of Clinical Sciences, NC StateExposure to environmental toxicants, a mechanism of hypermutability of cardiomyopathy-linked genes
2012Michael Sikes, Dept. of Microbiology, NC StateRedefining the network of transcriptional responses to environmental genotoxins
2012Tatyana I. Smirnova & Alex I Smirnova, Dept. of Chemistry, NC StateLinking free radical chemistry and toxicity of engineered nanomaterials
2011Greg Cope & Catherine LePrevost, Dept. of EM Toxicology, NC StateCulturally and literacy modified signage for environmental safety awareness
2011Alison Motsinger-Reif, Dept. of Statistics, NC State & Jane Hoppin, NIEHS and AHSVariance decompositions of genetic and exposure data pilot project