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Center for Human Health and the Environment

Seth Kullman

SK
Headshot of Seth Kullman

Professor

Department of Biological Sciences

Toxicology Building 1232

Bio

Dr. Kullman received his Ph.D. from the University of California at Davis in Pharmacology and
Toxicology (1996) and completed postdoctoral fellowship in the Department of Veterinary
Medicine at the University of California at Davis in 2000. Dr. Kullman joined the faculty of the
Integrated Toxicology Program at Duke University in 2000 and served as director of the Duke
University Superfund Center Functional Genomics Core (2004-2007). He then joined the faculty
of North Carolina State University in 2008 and is a Full Professor of Toxicology in the
Department of Biological Sciences. Dr. Kullman has a long-standing history of employing small
aquarium fish models in mechanistic toxicity studies with an emphasis on developmental
biology, endocrine biology and metabolic disruption. His laboratory employs molecular,
comparative and functional genomic approaches to examine how exposure to environmental
stressors (dys)regulate gene regulatory networks that govern critical steps of cell differentiation
and embryonic development. Much of his work is focused on nuclear receptors and ligand
activated transcription factor signaling. His recent studies are directed towards elucidating
coordinated cellular events facilitating stem cell commitment in relation to developmental
and/or degenerative bone diseases (osteogenesis imperfecta, osteoporosis, osteopenia), and
metabolic diseases (obesity, metabolic syndrome). Dr Kullman currently serves as Director of the
NIEHS Training Grant Molecular Pathways to Pathogenesis in Toxicology. He has over 85 peer-
reviewed publications, book chapters and technical reports. He has been a visiting scholar at the
Mount Desert Island Biological Laboratory and is currently a standing member of the EDD study
section for NIH.

Publications

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