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An Interdisciplinary Center with a Diverse Approach

We seek to understand how human health is impacted by environmental factors and how to reduce adverse impacts. 

At CHHE, we apply a systems biology approach, spanning biomolecules to human populations, to understand how environmental stressors impact human health. Our goal is to uncover the underlying mechanisms of disease and use this knowledge to mitigate adverse health outcomes.

CHHE: 100 strong, representing 3 Universities

We bring together 68 grant seeking faculty from 15 departments and 6 colleges at NC State, as well as 10 faculty from East Carolina’s Brody School of Medicine and 9 faculty from NC Central, in addition to our associate members and amazing staff.

PFAS SRP and CHHE work together to get answers on PCBs in building materials and reported health effects from invited guests at the Iowa Superfund Research Program

Fall Pilot Projects

Letter of Intent (pre-proposal abstract or concept paragraph) due September 1, 2024
Full proposal due September 15, 2024

View instructions, see eligibility, and funding award levels on the Pilot Project Program page.

CHHE provides focus, resources and leadership for interdisciplinary research that improves human health locally, nationally and globally.

Rob Smart

CHHE Founding Director

2023 Center Highlights


New Members


Seed money, travel funds & pilot project funds awarded


Projects supported by CHHE STC


Community grants funded


Publications by our members


NIH and NIEHS funded active grants

CHHE is committed to diversity, inclusion, equity, anti-racism, anti-oppression and environmental justice.  We challenge ourselves to identify and understand these inequities and to intentionally work to correct them.

CHHE is an NIEHS-funded Environmental Health Science Core Center.