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An Interdisciplinary Center with a Diverse Approach

We seek to understand how human health is impacted by environmental factors and how to reduce adverse impacts. 

At CHHE, we apply a systems biology approach, spanning biomolecules to human populations, to understand how environmental stressors impact human health. Our goal is to uncover the underlying mechanisms of disease and use this knowledge to mitigate adverse health outcomes.

CHHE: 100 strong, representing 3 Universities

We bring together 57 grant seeking faculty from 17 departments and 7 colleges at NC State, as well as 9 faculty from East Carolina’s Brody School of Medicine and 7 faculty from NC Central, in addition to our associate and advisory members and amazing staff.

Open Call for Pilot Projects

Letters of Intent (pre-proposal abstract or concept paragraph) due Feb 1.
Full proposals due Feb 15.

View instructions, see eligibility, and funding award levels on the Pilot Project Program page.

8th Annual CHHE Symposium

Perinatal Environmental Exposures and Later Life Disease: Biological Targets and Mechanisms

Tuesday, February 20, 2024

Talley Student Union, Piedmont/Mountains Ballroom
NC State University Main Campus
2610 Cates Ave, Raleigh 27606

CHHE provides focus, resources and leadership for interdisciplinary research that improves human health locally, nationally and globally.

Rob Smart

CHHE Founding Director

2023 Center Highlights


New Members


Seed money, travel funds & pilot project funds awarded


Projects supported by CHHE STC


Community grants funded


Publications by our members


NIH and NIEHS funded active grants

CHHE is committed to diversity, inclusion, equity, anti-racism, anti-oppression and environmental justice.  We challenge ourselves to identify and understand these inequities and to intentionally work to correct them.

CHHE is an NIEHS-funded Environmental Health Science Core Center.