Climate Justice in Rural Southeastern United States: Climate Change Impacts and Effects on Human Health

NC State educational researchers in the Departments of Applied Ecology and STEM Education recently published a review article exploring climate justice and human health in the Southeastern United States.  Climate justice is a movement to protect and empower at-risk populations who are disproportionately affected by climate change, and many populations in the Southeastern region of the United States fall into this “at-risk” category.  Science education doctoral candidate Kristie Gutierrez worked with CHHE COEC Director Dr. Catherine LePrevost to examine how […]

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Agricultural Pesticide Exposure and Chronic Kidney Disease: New Findings and More Questions

Researchers at NC State, NIEHS, and UNC Chapel Hill recently published the first article to link agricultural pesticide use to end stage renal disease. UNC doctoral student Jill Lebov worked with Dr. Jane Hoppin at NC State and researchers at NIEHS and UNC Chapel Hill to assess personal use of 39 different pesticides by over 55,000 farmers in the Agricultural Health Study (, a prospective study of farmers in North Carolina and Iowa. End stage renal disease is the last […]

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Jane A. Hoppin - Jill F. Lebov

Carolyn Mattingly Named University Faculty Scholar

Carolyn Mattingly is an Associate Professor in the Department of Biological Sciences and Co-Director of the CHHE’s Integrative Health Sciences Facility Core.  Her lab uses bioinformatics and comparative genomics approaches to understand the complex interactions between our environment and human health. She also leads the Comparative Toxicogenomics Database, which links research about chemicals genes and diseases to better predict how chemicals will affect our health. Carolyn wears many scholar hats, she is: an educator, teaching undergraduates in the classroom and […]

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“Telomeres are Partly Shielded from Ultraviolet-Induced Damage and Proficient for Nucleotide Excision Repair of Photoproducts”

North Carolina State University Researcher and CHHE Member, Hong Wang, and her colleagues at NC State and the University of Pittsburgh have found that telomeres are protected from ultraviolet (UV) light-induced DNA damage and that specific UV-induced photolesions in DNA are repaired more efficiently in the telomere than in the overall genome.  This work was partially supported by a CHHE Pilot Project awarded to Hong Wong.  Nonmelanoma skin cancer (NMSC) is the most common cancer in the United States. The […]

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“Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood”

A team of researchers led by North Carolina State University CHHE biologists Cathrine Hoyo and Randy Jirtle have found links between lead exposure in children and epigenetic alterations in regulatory regions of genes that are imprinted and known to be critical in growth regulation and brain development. These alterations seem to persist into adulthood, with more profound effects in males. Their study sheds more light on the long-term effects of early lead exposure on DNA and may help to develop […]

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